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RESEARCH PAPER
Prevalence of medication use in the postpartum period: A narrative review of current trends and implications for midwifery practice
 
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1
Delivery Room, General and Maternity Hospital ‘Helena Venizelou’, Athens, Greece
 
2
Department of Midwifery, Faculty of Health and Care Sciences, University of West Attica, Athens, Greece
 
3
Department of Nursing, Cyprus University of Technology, Limassol, Cyprus
 
 
Submission date: 2024-10-24
 
 
Final revision date: 2024-11-14
 
 
Acceptance date: 2024-11-17
 
 
Publication date: 2024-11-19
 
 
Corresponding author
Maria Tigka   

Delivery Room, General and Maternity Hospital ‘Helena Venizelou’, 2 Elenas Venizelou Street, 11521, Athens, Greece
 
 
ΕΛΕΥΘΩ 2024;23(4):8
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The postpartum period is a critical phase for maternal recovery and infant care. The aim of this narrative review is to explore the prevalence and indications of medication use in the postpartum period.

Methods:
This narrative review synthesized studies published in English over the past 20 years from electronic databases, including PubMed, Scopus, CINAHL, and the Cochrane Library, using key terms. Screening and data extraction were performed independently by two reviewers. Disagreements were resolved through discussion with a third reviewer. No formal quality assessment was performed.

Results:
Postpartum medication use is common, with prevalence rates varying between 34% and 100%, depending on the study population and setting. Medications for the nervous system (21.6%-99.6%), anti-infectives (27.6%-99.3%), and hematopoietic drugs (1.4%-91.7%) are frequently prescribed to manage pain, prevent infections, and support recovery from blood loss or prevent thrombosis. Musculoskeletal medications (14.1%-87.4%), drugs for the alimentary tract and metabolism (5.9%-79.5%), and treatments for the genitourinary system and hormonal preparations (7%-69.2%) are also commonly used, with significant variability among studies. In contrast, cardiovascular (2%-22.4%) and respiratory medications (0.8%-15%) are less commonly prescribed. The reasons for medication use include immediate recovery needs and the management of acute conditions. Medications are also used to manage chronic conditions.

Conclusions:
Medication use is highly prevalent in the postpartum period worldwide. A balanced approach, combining pharmacologic and non-pharmacologic care, is essential for safe recovery. Midwives are vital in helping mothers make informed choices. Future research should aim to establish standardized medication guidelines and evaluate safety to support evidence-based postpartum care.

CONFLICT OF INTEREST
The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none was reported.
FUNDING
There was no source of funding for this research.
DATA AVAILABILITY
Data sharing is not applicable to this article as no new data were created.
 
REFERENCES (28)
1.
ACOG Committee Opinion No. 736: Optimizing Postpartum Care. Obstet Gynecol. 2018;131(5):e140-e150. doi:10.1097/AOG.0000000000002633
 
2.
Al-Sawalha NA, Tahaineh L, Sawalha A, Almomani BA. Medication Use in Breastfeeding Women: A National Study. Breastfeed Med. 2016;11:386-391. doi:10.1089/bfm.2016.0044
 
3.
Guidance to Nurses and Midwives on Medication Management. An Bord Altranais; 2007. Accessed August 17, 2024. https://www.nmbi.ie/NMBI/media...
 
4.
Bérard A, Sheehy O. The Quebec Pregnancy Cohort--prevalence of medication use during gestation and pregnancy outcomes. PLoS One. 2014;9(4):e93870. doi:10.1371/journal.pone.0093870
 
5.
Ceulemans M, Foulon V, Panchaud A, et al. Self-Reported Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic: A Cross-Sectional Study in Five European Countries. Int J Environ Res Public Health. 2022;19(3):1389. doi:10.3390/ijerph19031389
 
6.
Chauhan G, Tadi P. Physiology, Postpartum Changes. StatPearls Publishing; 2024.
 
7.
Chaves RG, Lamounier JA, César CC. Association between duration of breastfeeding and drug therapy. Asian Pac J Trop Dis. 2011;1(3):216-221. doi:10.1016/s2222-1808(11)60032-7
 
8.
de Waard M, Blomjous BS, Hol MLF, et al. Medication Use During Pregnancy and Lactation in a Dutch Population. J Hum Lact. 2019;35(1):154-164. doi:10.1177/0890334418775630
 
9.
Fortinguerra F, Belleudi V, Poggi FR, et al. Medication prescriptions before, during and after pregnancy in Italy: a population-based study. Ann Ist Super Sanita. 2021;57(3):249-258. doi:10.4415/ANN_21_03_09
 
10.
Meyling MMG, Frieling ME, Vervoort JPM, Feijen-de Jong EI, Jansen DEMC. Health problems experienced by women during the first year postpartum: A systematic review. Eur J Midwifery. 2023;7(December):1-20. doi:10.18332/ejm/173417
 
11.
Philosophy and Model of Midwifery Care. International Confederation of Midwives; 2005. Updated 2014. Accessed August 17, 2024. https://internationalmidwives....
 
12.
Ingram MA, Brady S, Peacock AS. The barriers to offering non-pharmacological pain management as an initial option for laboring women: A review of the literature. Eur J Midwifery. 2022;6(June):1-12. doi:10.18332/ejm/149244
 
13.
Lopez-Gonzalez DM, Kopparapu AK. Postpartum Care of the New Mother. StatPearls Publishing; 2024.
 
14.
Lutz BH, Bassani DG, Miranda VIA, et al. Use of Medications by Breastfeeding Women in the 2015 Pelotas (Brazil) Birth Cohort Study. Int J Environ Res Public Health. 2020;17(2):568. doi:10.3390/ijerph17020568
 
15.
Luxey X, Lemoine A, Dewinter G, et al. Acute pain management after vaginal delivery with perineal tears or episiotomy. Reg Anesth Pain Med. doi:10.1136/rapm-2024-105478
 
16.
Oshikoya KA, Akionla IO, Senbanjo IO, Oreagba IA, Ogunleye OO. Medicines used in pregnancy, childbirth and lactation in a teaching hospital in Lagos, Nigeria. Sri Lanka J Obstet Gyn. 2012;34(3):84. doi:10.4038/sljog.v34i3.4881
 
17.
Pallavi PP, Rajesh K, Purushothama RK, Ravindra RK, Rama DV. Drug use pattern among lactating women in a tertiary care teaching hospital. Journal of Global Trends in Pharmaceutical Sciences. 2013;4(3):1138-1143.
 
18.
Pappa E, Kontodimopoulos N, Papadopoulos AA, Tountas Y, Niakas D. Prescribed-drug utilization and polypharmacy in a general population in Greece: association with sociodemographic, health needs, health-services utilization, and lifestyle factors. Eur J Clin Pharmacol. 2011;67(2):185-192. doi:10.1007/s00228-010-0940-0
 
19.
Sadiq IZ. Lifestyle medicine as a modality for prevention and management of chronic diseases. J Taibah Univ Med Sci. 2023;18(5):1115-1117. doi:10.1016/j.jtumed.2023.04.001
 
20.
Saha MR, Ryan K, Amir LH. Postpartum women's use of medicines and breastfeeding practices: a systematic review. Int Breastfeed J. 2015;10:28. doi:10.1186/s13006-015-0053-6
 
21.
Saharoy R, Potdukhe A, Wanjari M, Taksande AB. Postpartum Depression and Maternal Care: Exploring the Complex Effects on Mothers and Infants. Cureus. 2023;15(7):e41381. doi:10.7759/cureus.41381
 
22.
Silveira MPT, Miranda VIA, Silveira MFD, Pizzol TDSD, Mengue SS, Bertoldi AD. Drug use in delivery hospitalization: Pelotas births cohort, 2015. Rev Saude Publica. 2019;53:51. doi:10.11606/S1518-8787.2019053000913
 
23.
Stultz EE, Stokes JL, Shaffer ML, Paul IM, Berlin CM. Extent of medication use in breastfeeding women. Breastfeed Med. 2007;2(3):145-151. doi:10.1089/bfm.2007.0010
 
24.
Tigka M, Metallinou D, Nanou C, Iliodromiti Z, Gryparis A, Lykeridou K. Medication Intake as a Factor for Non-Initiation and Cessation of Breastfeeding: A Prospective Cohort Study in Greece during the COVID-19 Pandemic. Children (Basel). 2023;10(3):586. doi:10.3390/children10030586
 
25.
Ubom EO, Wang C, Klocksieben F, et al. Enhanced recovery protocol after cesarean delivery: impact on opioid use and pain perception. AJOG Glob Rep. 2023;3(3):100220. doi:10.1016/j.xagr.2023.100220
 
26.
Walker LO, Murphey CL, Nichols F. The Broken Thread of Health Promotion and Disease Prevention for Women During the Postpartum Period. J Perinat Educ. 2015;24(2):81-92. doi:10.1891/1058-1243.24.2.81
 
27.
Anatomical Therapeutic Chemical (ATC) Classification. World Health Organization. Accessed August 17, 2024. https://www.who.int/tools/atc-...
 
28.
Yaya Tessema G, Ayele G, Fikadu Tessema K, Gendisha Ukke G, Godana Boynito W. Knowledge of postpartum complications and associated factors among women who gave birth in the last 12 months in Arba Minch Town, Southern Ethiopia, 2019: A community-based cross-sectional study. PLoS One. 2023;18(2):e0281242. doi:10.1371/journal.pone.0281242
 
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